Hydrochloric Acid → HCID 11997576, compound

Participants

Reaction Steps

Diastereomer 2: 30 mg of the amine was isolated and converted into its di-hydrochloride salt by treating a methanolic solution of the amine with 145 μL of 1 N HCl in ether. The yellow solid was collected by vacuum filtration, washed with ethyl acetate and hexane, and dried under vacuum to afford N-{[(3R)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]methyl}-N-{[(2S)-8-methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl]methyl}amine as a yellow powder; mp 218-221 (d); MS (ES) m/z=414 [M+H]+.

Provenance & Evidence