反应详情

Diethyl 2-[2-(2,3-difluorophenyl)-2-oxoethyl]-2-hydroxymalonate (18.50 g, 56.1 mmol) and hydrazine monohydrochloride (4.03 g, 58.8 mmol) were stirred at reflux in ethanol (300 mL) for 96 h, and then evaporated to dryness to afford the title compound as a solid.

1. customevaporated to dryness