HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl bromoacetate → HCID 11584039, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | HCID 11582509 | HCID 11582509 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 11584039 | HCID 11584039 | — |
Reaction Steps
Compound 30 was prepared from 117 mg 29 by stirring in 5 mL dry dichloromethane adding 100 μl N,N-diisopropylethylamine and 25 μl bromoacetic acid methylester overnight at room temperature. After aqueous work-up the product 30 was isolated by SiO2 chromatography (5-20% ethylacetate/hexane) and 23 mg of an off white solid was obtained (21% yield). MS (M+1)=492.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07297796B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-7b8dab7e2b174cf68537eb20eea08b25 |
| Source note | uspto-grants-2007_11 |