HCID 59000784, compound → HCID 52942491, compound

Participants

Reaction Steps

HCO2NH4 (29 mg, 0.459 mmol) was added to a suspension of 9 (50 mg, 0.092 mmol) and 10% Pd/C (10 mg) in EtOH (10 mL). The reaction mixture was stirred at ambient temperature for 24 h. The reaction mixture was filtered through celite and the filtrate was concentrated in vacuo. The resulting residue was triturated in (1:1) Et2O/hexane and the resulting precipitate was collected by vacuum filtration to provide the title compound as a yellow solid. 1H NMR (DMSO-d6) δ 0.84 (t, J=7.1 Hz, 3H), 1.09 (t, J=7.0 Hz, 3H), 3.39 (m, 4H), 3.51 (q, J=7.1 Hz, 2H), 3.67 (m, 4H), 4.07 (q, J=7.2 Hz, 2H), 6.60 (d, J=8.4 Hz, 2H), 6.80 (s, 1H), 7.27 (d, J=8.3 Hz, 2H), 7.44 (m, 5H). Mass Spectrum (ESI+) m/e=515.3 (M+H).

Provenance & Evidence