反应详情

10% Pd/C (100 mg) is added to a Parr bottle containing 1-(3-ethylamino-4-nitro-phenyl)-ethanone (0.98 g, 4.7 mmol) in ethanol (40 mL). The Parr bottle is sealed in a mechanical shaker, evacuated, and then purged with nitrogen followed by hydrogen. The system is pressurized to 50 PSI of hydrogen at room temperature and mechanical shaking engaged. After 2 hours, shaking is stopped, and the system purged with nitrogen prior to opening the vessel. The reaction mixture is filtered through celite, concentrated in vacuo, to give 1-(4-amino-3-ethylamino-phenyl)-ethanone.

1. customThe Parr bottle is sealed in a mechanical shaker
2. customevacuated
3. custompurged with nitrogen
4. customis pressurized to 50 PSI of hydrogen at room temperature
5. stirringshaking
6. customthe system purged with nitrogen
7. filtrationThe reaction mixture is filtered through celite
8. concentrationconcentrated in vacuo