Morpholine → HCID 69267290, compound

Participants

Reaction Conditions

Reaction Steps

The crude product of example 22 (b) (˜5.6 mmol) was dissolved in morpholine (10 mL) and heated to 57° C. while stirring under argon for 1 h. The solvent was pumped off, and the residue was partitioned between EtOAc and water. The organic phase was washed with brine, dried (Na2SO4), and concentrated. The crude product was purified by flash chromatography (silica gel, 2–5% MeOH/CH2Cl2) to give the title compound as a white solid. ES (+) MS m/e=259 (MH+)

Provenance & Evidence