HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Sodium difluorosulfoacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate | HCID 547667 | — |
| Solvent | Water | HCID 962 | — |
| Product | Sodium difluorosulfoacetate | HCID 86607434 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
230 Parts of 30% aqueous sodium hydroxide solution was added dropwise into a mixtuxe of 100 parts of methyl difluoro(fluorosulfonyl)acetate and 250 parts of ion-exchanged water in a ice bath. The added mixture was heated and refluxed at 100° C. for 25 hours. After cooling, the cooled mixture was neutralized with 88 parts of conc. hydrochloric acid and concentrated to obtain 158.4 parts of sodium difluorosulfoacetate (containing inorganic salt, purity: 65.1%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07301047B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-55d15ca078ae4cb59be02d097d7e3618 |
| Source note | uspto-grants-2007_11 |