HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Pyrenebutanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | gamma-Oxo-1-pyrenebutyric acid | HCID 82011 | — |
| Solvent | Diethylene Glycol | HCID 8117 | — |
| Product | 1-Pyrenebutanoic acid | HCID 76977 | 71.1% |
Reaction Steps
1 g (2.78 mmol) of 4-oxo-4-(pyrene-1-yl)-butyric acid was dissolved in 30 ml diethylene glycol and 0.5 9 (10 mmol) of hydrazine hydrate as well as 0.56 g (10 mmol) of KOH added thereto. The reaction solution was heated under reflux for 2 hours and then poured onto iced hydrochloric acid (25%), forming a yellow precipitate. Filtration of the solid and recrystallization from EtOH yielded 570 mg (71%) of 4-(pyrene-1-yl)-butyric acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07301043B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-8288b84e067e4bc2b4398109971fc669 |
| Source note | uspto-grants-2007_11 |