Isobutyraldehyde → HCID 58691309, compound

Participants

Reaction Steps

N-(2-(6-(2-Acetamidobenzo[d]thiazol-4-yloxy)pyrimidin-4-yl)-5-(trifluoromethyl)phenyl)piperidine-2-carboxamide, Example 49(a), (0.50 g, 0.90 mmol) was reacted with isobutyraldehyde (0.16 mL, 1.8 mmol, Aldrich) under the conditions of Example 3(d) to give the title compound as a white solid. MS (ESI, pos. ion) m/z: 613 (M+1). Mp: 153.4-154.9° C.

Provenance & Evidence