HuagongsheHuagongshe Chemistry Print Report · For research reference only
Furan → Phosphonic acid, 2-furanyl-, diethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Furan | HCID 8029 | — |
| Reactant | Diethyl chlorophosphate | HCID 13139 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Phosphonic acid, 2-furanyl-, diethyl ester | HCID 12485182 | — |
Reaction Conditions
| Temperature | -78 °C |
|---|
Reaction Steps
A solution of furan (1 mmol) in diethyl ether was treated with TMEDA (N,N,N′N′-tetramethylethylenediamine) (1 mmol) and nBuLi (2 mmol) at −78° C. The solution was stirred for 0.5 h. at −78° C. and diethyl chlorophosphate was added and stirred for another 1 h. Extraction and distillation produced diethyl 2-furanphosphonate as a clear oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06284748B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-bfd67d664cb144f5aa601973587111a5 |
| Source note | uspto-grants-2001_09 |