Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Adenine | HCID 190 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 9-(Phenylmethyl)-9H-purin-6-amine | HCID 20262 | — |
Reaction Steps
Adenine (1 mmol) in DMF was treated with sodium hydride (1.2 mmol) followed by benzyl bromide (1.2 mmol) at room temperature under nitrogen. The resulting mixture was warmed at 100° C. for 2 h. The cooled reaction mixture was evaporated to dryness. Extraction and chromatography afforded N9-benzyladenine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06284748B1 |
|---|
| Source dataset | uspto-grants-2001_09 |
|---|
| ORD ID | ord-0200b462343b426596d1c64fd004cbca |
|---|
| Source note | uspto-grants-2001_09 |
|---|
