HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → N9-phenethyl-8-hydroxymethyladenine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | N9-phenethyl-8-methoxycarbonyladenine | HCID 42637713 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N9-phenethyl-8-hydroxymethyladenine | HCID 42637018 | — |
Reaction Steps
A solution of N9-phenethyl-8-methoxycarbonyladenine (1 mmol) in tetrahydrofuran was treated with lithium aluminum hydride (1 mmol) at 0° C. for 1 h. Extraction and chromatography gave N9-phenethyl-8-hydroxymethyl-adenine as a white solid. TLC: Rf=0.31, 10% MeOH—CH2Cl2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06284748B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-ca9ecbfe7b2d49d98e6758dad26748b4 |
| Source note | uspto-grants-2001_09 |