HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 86602091, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetoxyacetyl chloride | HCID 26297 | — |
| Reactant | HCID 22274990 | HCID 22274990 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 86602091 | HCID 86602091 | — |
Reaction Steps
A solution of 6-chloro-5-amino-4-(neopentylamino)pyrimidine (1 mmol) in diethyl ether was treated with pyridine (3 mmol), and acetoxyacetyl chloride (1.2 mmol) at 25° C. for 12 h. Extraction and chromatography afforded 6-chloro-5-acetoxyacetyl-amino-4-neopentylaminopyrimidine as a yellow solid. TLC: Rf=0.18, 30% EtOAc-hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06284748B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-ba911d9459c04159a972fada7cadf4a8 |
| Source note | uspto-grants-2001_09 |