HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 54539253, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 54013252 | HCID 54013252 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | HCID 54539253 | HCID 54539253 | — |
Reaction Steps
A solution of 6-chloro-8-acetoxymethyl-N9-neopentylpurine (1 mmol) in THF-water was treated with aqueous sodium hydroxide (1.5 mmol) at 0° C. for 0.5 h. Extraction and chromatography afforded 6-chloro-8-hydroxymethyl-N9-neopentylpurine as a yellow gel. TLC: Rf=0.38, 33% EtOAc-hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06284748B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-4ba335e356aa40949cd1e8e4d36b47a7 |
| Source note | uspto-grants-2001_09 |