HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl chlorophosphate → HCID 22274954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl chlorophosphate | HCID 13139 | — |
| Reactant | 3,4-dichlorofuran-2-carboxylic acid | HCID 234857 | — |
| Reactant | Lithium diisopropylamide | HCID 2724682 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 22274954 | HCID 22274954 | — |
Reaction Steps
A solution of 3,4-dichloro-2-furoic acid (1 mmol) in diethyl ether was treated with LDA (3 mmol) at −78° C. for 30 min and then treated with diethyl chlorophosphate (3.5 mmol) at −78° C. for 1 h. The reaction was quenched and extracted to give 5-diethylphosphono-3,4-dichloro-2-furoic acid as a yellow foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06284748B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-4d82a43834d44fe1ab4bce5dd0190039 |
| Source note | uspto-grants-2001_09 |