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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1594692Generated: November 4, 2026

4-Toluenesulfonyl chloride → 4-(1-Tosylpyrrolidin-2-yl)pyridine

https://huagongshe.com/reaction/1594692

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Toluenesulfonyl chlorideHCID 7397—
Reactant4-(Pyrrolidin-2-yl)pyridineHCID 2771664—
Product4-(1-Tosylpyrrolidin-2-yl)pyridineHCID 12132447—

Reaction Steps

The title compound, pale brown solid, m.p. 158° C. and MS: m/e=302 (M+) was prepared in accordance with the general method of example 1e from (RS)-4-(2-pyrrolidinyl)-pyridine and toluene-4-sulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06284785B1
Source datasetuspto-grants-2001_09
ORD IDord-c83105c6ab684c6589634d7088274eab
Source noteuspto-grants-2001_09