4-Chlorobenzenesulfonyl chloride → HCID 21706737, compound

HRID 1594708Notes

Reaction equation

HRID 1594708 reaction equation
[C:1]1([CH3:12])[CH:6]=[CH:5][C:4]([CH:7]2[CH2:11][CH2:10][CH2:9][NH:8]2)=[CH:3][CH:2]=1.[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20](Cl)(=[O:22])=[O:21])=[CH:16][CH:15]=1>>[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([N:8]2[CH2:9][CH2:10][CH2:11][CH:7]2[C:4]2[CH:5]=[CH:6][C:1]([CH3:12])=[CH:2][CH:3]=2)(=[O:22])=[O:21])=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 35631342-(4-methylphenyl)pyrrolidine

Product 1

HCID 21706737HCID 21706737, compound

Procedure

The title compound, white solid, m.p. 129° C. and MS: m/e=335 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-p-tolyl-pyrrolidine and 4-chloro-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-a6dce90ddd164acbb9a2c4894e5d9587
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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