4-(Propan-2-yl)benzene-1-sulfonyl chloride → HCID 21706747, compound

HRID 1594709Notes

Reaction equation

HRID 1594709 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][NH:9]2)=[CH:4][CH:3]=1.[CH:13]([C:16]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1)([CH3:15])[CH3:14]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][N:9]2[S:22]([C:19]2[CH:20]=[CH:21][C:16]([CH:13]([CH3:15])[CH3:14])=[CH:17][CH:18]=2)(=[O:24])=[O:23])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 27348824-(Propan-2-yl)benzene-1-sulfonyl chlorideHCID 38655602-(4-Fluorophenyl)pyrrolidine

Product 1

HCID 21706747HCID 21706747, compound

Procedure

The title compound, white solid, m.p. 77° C. and MS: m/e=347 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-fluoro-phenyl)-pyrrolidine and 4-isopropyl-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-d10662582f914b0d968ef686a5a66d3b
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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