4-Chlorobenzenesulfonyl chloride → HCID 21706725, compound

HRID 1594711Notes

Reaction equation

HRID 1594711 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:13][CH2:12][CH2:11][NH:10]2)=[CH:5][CH:4]=1.[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21](Cl)(=[O:23])=[O:22])=[CH:17][CH:16]=1>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21]([N:10]2[CH2:11][CH2:12][CH2:13][CH:9]2[C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)(=[O:23])=[O:22])=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 37569572-(4-methoxyphenyl)pyrrolidine

Product 1

HCID 21706725HCID 21706725, compound

Procedure

The title compound, white solid, m.p. 133° C. and MS: m/e=352 (M+H+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-methoxy-phenyl)-pyrrolidine and 4-chloro-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-86a39d72c5314914bb28d3c9c15faf32
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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