4-Cyanobenzenesulfonyl chloride → HCID 21706719, compound

HRID 1594719Notes

Reaction equation

HRID 1594719 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][NH:9]2)=[CH:4][CH:3]=1.[C:13]([C:15]1[CH:20]=[CH:19][C:18]([S:21](Cl)(=[O:23])=[O:22])=[CH:17][CH:16]=1)#[N:14]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][N:9]2[S:21]([C:18]2[CH:17]=[CH:16][C:15]([C:13]#[N:14])=[CH:20][CH:19]=2)(=[O:23])=[O:22])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 394974-Cyanobenzenesulfonyl chlorideHCID 38655602-(4-Fluorophenyl)pyrrolidine

Product 1

HCID 21706719HCID 21706719, compound

Procedure

The title compound, off-white solid, m.p. 147° C. and MS: m/e=330 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-fluoro-phenyl)-pyrrolidine and 4-cyano-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-e8ad0810c6db4ef8b0265f0450c3ff34
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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