4-Chlorobenzenesulfonyl chloride → HCID 21706774, compound

HRID 1594720Notes

Reaction equation

HRID 1594720 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]2[CH2:13][CH2:12][CH2:11][NH:10]2)[CH:6]=[CH:7][CH:8]=1.[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21](Cl)(=[O:23])=[O:22])=[CH:17][CH:16]=1>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21]([N:10]2[CH2:11][CH2:12][CH2:13][CH:9]2[C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=2)(=[O:23])=[O:22])=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 36138242-(3-Methoxyphenyl)pyrrolidine

Product 1

HCID 21706774HCID 21706774, compound

Procedure

The title compound, white solid, m.p. 95° C. and MS: m/e=351 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(3-methoxy-phenyl)-pyrrolidine and 4-chloro-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-d44366e8b4e84db4b45ef9ba07924933
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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