4-Chlorobenzenesulfonyl chloride → HCID 21706735, compound

HRID 1594732Notes

Reaction equation

HRID 1594732 reaction equation
[F:1][C:2]([F:15])([F:14])[C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:13][CH2:12][CH2:11][NH:10]2)=[CH:5][CH:4]=1.[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([S:23](Cl)(=[O:25])=[O:24])=[CH:19][CH:18]=1>>[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([S:23]([N:10]2[CH2:11][CH2:12][CH2:13][CH:9]2[C:6]2[CH:7]=[CH:8][C:3]([C:2]([F:1])([F:14])[F:15])=[CH:4][CH:5]=2)(=[O:25])=[O:24])=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 37011532-[4-(trifluoromethyl)phenyl]pyrrolidine

Product 1

HCID 21706735HCID 21706735, compound

Procedure

The title compound, white solid, m.p. 107° C. and MS: m/e=369 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-trifluoromethyl-phenyl)-pyrrolidine and 4-chloro-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-48d42cead4df42418ea67a49e8a4683c
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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