4-Chlorobenzenesulfonyl chloride → HCID 21706733, compound

HRID 1594736Notes

Reaction equation

HRID 1594736 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]1[CH2:12][CH2:11][CH2:10][NH:9]1.[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20](Cl)(=[O:22])=[O:21])=[CH:16][CH:15]=1>>[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([N:9]2[CH2:10][CH2:11][CH2:12][CH:8]2[C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[F:1])(=[O:22])=[O:21])=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 36133062-(2-fluorophenyl)pyrrolidine

Product 1

HCID 21706733HCID 21706733, compound

Procedure

The title compound, white solid, m.p. 134° C. and MS: m/e=340.2 (M+H+) was prepared in accordance with the general method of example 1e from (RS)-2-(2-fluoro-phenyl)-pyrrolidine and 4-chloro-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-14688f01acac40b89d59d70fee632cf6
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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