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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1594737Generated: October 30, 2026

4-Fluorobenzenesulfonyl chloride → 2-(2-Fluorophenyl)-1-[(4-fluorophenyl)sulfonyl]pyrrolidine

https://huagongshe.com/reaction/1594737

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzenesulfonyl chlorideHCID 9588—
Reactant2-(2-fluorophenyl)pyrrolidineHCID 3613306—
Product2-(2-Fluorophenyl)-1-[(4-fluorophenyl)sulfonyl]pyrrolidineHCID 21706714—

Reaction Steps

The title compound, white solid, m.p. 108° C. and MS: m/e=324.2 (M+H+) was prepared in accordance with the general method of example 1e from (RS)-2-(2-fluoro-phenyl)-pyrrolidine and 4-fluoro-benzenesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06284785B1
Source datasetuspto-grants-2001_09
ORD IDord-e3faf9edae35418da786147414e9f18d
Source noteuspto-grants-2001_09