4-Chlorobenzenesulfonyl chloride → HCID 21706715, compound

HRID 1594739Notes

Reaction equation

HRID 1594739 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([CH:6]2[CH2:10][CH2:9][CH2:8][NH:7]2)=[CH:2]1.[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([S:18](Cl)(=[O:20])=[O:19])=[CH:14][CH:13]=1>>[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([S:18]([N:7]2[CH2:8][CH2:9][CH2:10][CH:6]2[C:3]2[CH:4]=[CH:5][S:1][CH:2]=2)(=[O:20])=[O:19])=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 39886722-thiophen-3-ylpyrrolidine

Product 1

HCID 21706715HCID 21706715, compound

Procedure

The title compound, white solid, m.p. 120° C. and MS: m/e=328.1 (M+H+) was prepared in accordance with the general method of example 1e from (RS)-2-thien-3-yl-pyrrolidine and 4-chloro-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-1c4ffa88365746d5897a44dc1bbc0b7b
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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