2-Mesitylenesulfonyl chloride → HCID 21706717, compound

HRID 1594744Notes

Reaction equation

HRID 1594744 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][NH:9]2)=[CH:4][CH:3]=1.[CH3:13][C:14]1[CH:19]=[C:18]([CH3:20])[CH:17]=[C:16]([CH3:21])[C:15]=1[S:22](Cl)(=[O:24])=[O:23]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][N:9]2[S:22]([C:15]2[C:16]([CH3:21])=[CH:17][C:18]([CH3:20])=[CH:19][C:14]=2[CH3:13])(=[O:24])=[O:23])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 130462-Mesitylenesulfonyl chlorideHCID 38655602-(4-Fluorophenyl)pyrrolidine

Product 1

HCID 21706717HCID 21706717, compound

Procedure

The title compound, white solid, m.p. 111° C. and MS: m/e=347 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-fluoro-phenyl)-pyrrolidine and 2,4,6-trimethyl-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-42198c784e4340c8b383702c14a6986d
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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