2-Cyanobenzenesulfonyl Chloride → HCID 21706701, compound

HRID 1594748Notes

Reaction equation

HRID 1594748 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][NH:9]2)=[CH:4][CH:3]=1.[C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[S:21](Cl)(=[O:23])=[O:22])#[N:14]>>[C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[S:21]([N:9]1[CH2:10][CH2:11][CH2:12][CH:8]1[C:5]1[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=1)(=[O:23])=[O:22])#[N:14]

Participants

3

Reactant 2

HCID 5223472-Cyanobenzenesulfonyl ChlorideHCID 38655602-(4-Fluorophenyl)pyrrolidine

Product 1

HCID 21706701HCID 21706701, compound

Procedure

The title compound, light green solid, m.p. 101° C. and MS: m/e=330 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-fluoro-phenyl)-pyrrolidine and 2-cyano-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-c491bc3cce3b40a8a43b83d96d06dee9
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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