4-Fluorobenzenesulfonyl chloride → HCID 21706763, compound

HRID 1594751Notes

Reaction equation

HRID 1594751 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH:9]1[CH2:13][CH2:12][CH2:11][NH:10]1.[F:14][C:15]1[CH:20]=[CH:19][C:18]([S:21](Cl)(=[O:23])=[O:22])=[CH:17][CH:16]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH:9]1[CH2:13][CH2:12][CH2:11][N:10]1[S:21]([C:18]1[CH:19]=[CH:20][C:15]([F:14])=[CH:16][CH:17]=1)(=[O:23])=[O:22]

Participants

3

Reactant 2

HCID 95884-Fluorobenzenesulfonyl chlorideHCID 3990120HCID 3990120, compound

Product 1

HCID 21706763HCID 21706763, compound

Procedure

The title compound, white solid, m.p. 134° C. and MS: m/e=333 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(2,4-dimethyl-phenyl)-pyrrolidine and 4-fluoro-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-e4114bfe2d124f6fafaed9efdc461ebc
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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