4-Fluorobenzenesulfonyl chloride → HCID 21706771, compound

HRID 1594753Notes

Reaction equation

HRID 1594753 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]1[CH2:10][CH2:9][CH2:8][NH:7]1.[F:11][C:12]1[CH:17]=[CH:16][C:15]([S:18](Cl)(=[O:20])=[O:19])=[CH:14][CH:13]=1>>[F:11][C:12]1[CH:17]=[CH:16][C:15]([S:18]([N:7]2[CH2:8][CH2:9][CH2:10][CH:6]2[C:2]2[O:1][CH:5]=[CH:4][CH:3]=2)(=[O:20])=[O:19])=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 95884-Fluorobenzenesulfonyl chlorideHCID 36759882-(furan-2-yl)pyrrolidine

Product 1

HCID 21706771HCID 21706771, compound

Procedure

The title compound, white solid, m.p. 69° C. and MS: m/e=295 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-furan-2-yl-pyrrolidine and 4-fluoro-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-1b64584746af4f99b1a6990d33f3101f
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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