Benzenesulfonyl chloride → HCID 21706770, compound

HRID 1594755Notes

Reaction equation

HRID 1594755 reaction equation
[F:1][C:2]([F:15])([F:14])[C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:13][CH2:12][CH2:11][NH:10]2)=[CH:5][CH:4]=1.[C:16]1([S:22](Cl)(=[O:24])=[O:23])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:16]1([S:22]([N:10]2[CH2:11][CH2:12][CH2:13][CH:9]2[C:6]2[CH:7]=[CH:8][C:3]([C:2]([F:1])([F:14])[F:15])=[CH:4][CH:5]=2)(=[O:24])=[O:23])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 7369Benzenesulfonyl chlorideHCID 37011532-[4-(trifluoromethyl)phenyl]pyrrolidine

Product 1

HCID 21706770HCID 21706770, compound

Procedure

The title compound, white solid, m.p. 95° C. and MS: m/e=355 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-trifluoromethyl-phenyl)-pyrrolidine and benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-c7bbd1f523c24dfe835125bcaf42a45e
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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