4-Chlorobenzenesulfonyl chloride → HCID 21706750, compound

HRID 1594759Notes

Reaction equation

HRID 1594759 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([C@@H:9]2[CH2:13][CH2:12][CH2:11][NH:10]2)=[CH:5][CH:4]=1)[CH3:2].[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21](Cl)(=[O:23])=[O:22])=[CH:17][CH:16]=1>>[CH2:1]([C:3]1[CH:4]=[CH:5][C:6]([CH:9]2[CH2:13][CH2:12][CH2:11][N:10]2[S:21]([C:18]2[CH:19]=[CH:20][C:15]([Cl:14])=[CH:16][CH:17]=2)(=[O:23])=[O:22])=[CH:7][CH:8]=1)[CH3:2]

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 40466179HCID 40466179, compound

Product 1

HCID 21706750HCID 21706750, compound

Procedure

The title compound, white solid, m.p. 94° C. and MS: m/e=350.3 (M+) was prepared in accordance with the general method of example 1e from (S)-2-(4-ethyl-phenyl)-pyrrolidine and 4-chloro-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-eda4ff68edf04b01ace1fe5b04e9e1cc
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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