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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1594761Generated: November 1, 2026

4-Toluenesulfonyl chloride → HCID 12132445, compound

https://huagongshe.com/reaction/1594761

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Toluenesulfonyl chlorideHCID 7397—
Reactant(R)-2-(4-Fluorophenyl)pyrrolidineHCID 7047818—
SolventChloroformHCID 6212—
ProductHCID 12132445HCID 12132445—

Reaction Steps

The title compound, white solid, m.p. 136° C., [a]D20=174° (c=0.1 in CHCl3) and MS: m/e=319 (M+) was prepared in accordance with the general method of example 1e from (R)-2-(4-fluoro-phenyl)-pyrrolidine and toluene-4-sulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06284785B1
Source datasetuspto-grants-2001_09
ORD IDord-8ccbd26c04ec4fd9b1bf4af715ef4170
Source noteuspto-grants-2001_09