反应详情

To a solution of 3-ethyl-1-(2-methoxy-ethyl)-3-(3-benzyloxy-phenyl)-azepan-2-one, as described above in Step A, (0.120 g, 0.412 mmol) in MeOH (20 mL) was added 10% Pd on C (0.025 g), and the mixture was hydrogenated under a H2 balloon at ambient temperature for 48 h. The reaction mixture was filtered, and the filtrate concentrated to dryness to give the title compound.

1. customat ambient temperature
2. customfor 48 h
3. filtrationThe reaction mixture was filtered
4. concentrationthe filtrate concentrated to dryness