HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 21707624, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Sulfoxonium, trimethyl-, iodide (1:1) | HCID 74498 | — |
| Reactant | 3-Penten-2-one, 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)- | HCID 103210 | — |
| Product | HCID 21707624 | HCID 21707624 | 45% |
Reaction Steps
11.3 g (55 mmol) of 3-methyl-5(2,2,3-trimethylcyclopent-3enyl)-pent-3-en-2-one was cyclopropanated with 14.1 g (63 mmol) of trimethylsulfoxonium iodide and 3.08 g (64 mmol) of 50% oil suspension of sodium hydride according to Example 11a giving 5.4 g (45% yield) of 1-[1-methyl-2(2,2,3trimethylcyclopent-3-enylmethyl)cyclopropyl]ethanone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06284929B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-cf5fd9efc6f84e539a5368f6036c7ec0 |
| Source note | uspto-grants-2001_09 |