HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-Lys(Z)-OH → 3alpha-N-(Nalpha-tert-butyloxycarbonyl-Nepsilon-benzyloxycarbonyl-L-lysyl)aminocholestane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-Lys(Z)-OH | HCID 2724765 | — |
| Reactant | 3Alpha-aminocholestane | HCID 10872780 | — |
| Product | 3alpha-N-(Nalpha-tert-butyloxycarbonyl-Nepsilon-benzyloxycarbonyl-L-lysyl)aminocholestane | HCID 70251499 | — |
Reaction Steps
By using Nα-tert-butyloxycarbonyl-Nε-benzyloxycarbonyl-L-lysine (760 mg, 2.00 mmol) and 3α-aminocholestane (853 mg, 2.20 mmol), the title compound was obtained in the same manner as in Synthetic Example BB 1 (1.57 g, quantitative).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06288041B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-8c77b2e8750a46b58564cf6f1e9fc9a8 |
| Source note | uspto-grants-2001_09 |