HRID1595194

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID70373

Benzoic acid, 2-(acetylamino)-4-nitro-

C9H8N2O5

结构：CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4C[C@H](N)CC[C@]4(C)[C@H]3CC[C@]12C

HCID10872780

未命名化合物

PRODUCTS

生成物

结构：CC(=O)Nc1cc([N+](=O)[O-])ccc1C(=O)N[C@@H]1CC[C@@]2(C)C(CC[C@H]3[C@@H]4CC[C@H]([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@@H]32)C1

HCID54038007

未命名化合物

收率 37%

PROCEDURE

实验过程

By using 2-acetamido-4-nitrobenzoic acid (800 mg, 3.57 mmol) and 3α-aminocholestane (1.4 g, 3.61 mmol), the title compound was obtained in the same manner as in Synthetic Example BB1 (784 mg, yield; 37.0%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-398f09d07acb4be1bf1298798d7ba3b3
来源数据集: uspto-grants-2001_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06288041B1
来源说明: uspto-grants-2001_09

反应 SMILES

[C:1]([NH:4][C:5]1[CH:13]=[C:12]([N+:14]([O-:16])=[O:15])[CH:11]=[CH:10][C:6]=1[C:7]([OH:9])=O)(=[O:3])[CH3:2].[NH2:17][C@@H:18]1[CH2:42][CH2:41][C@@:40]2([CH3:43])[CH:20]([CH2:21][CH2:22][C@@H:23]3[C@@H:39]2[CH2:38][CH2:37][C@@:36]2([CH3:44])[C@H:24]3[CH2:25][CH2:26][C@@H:27]2[C@H:28]([CH3:35])[CH2:29][CH2:30][CH2:31][CH:32]([CH3:34])[CH3:33])[CH2:19]1>>[C:1]([NH:4][C:5]1[CH:13]=[C:12]([N+:14]([O-:16])=[O:15])[CH:11]=[CH:10][C:6]=1[C:7]([NH:17][C@@H:18]1[CH2:42][CH2:41][C@@:40]2([CH3:43])[CH:20]([CH2:21][CH2:22][C@@H:23]3[C@@H:39]2[CH2:38][CH2:37][C@@:36]2([CH3:44])[C@H:24]3[CH2:25][CH2:26][C@@H:27]2[C@H:28]([CH3:35])[CH2:29][CH2:30][CH2:31][CH:32]([CH3:34])[CH3:33])[CH2:19]1)=[O:9])(=[O:3])[CH3:2]