Silicon tetrachloride → 3-Cyano-2,4,5-trifluoro-benzoyl chloride

Participants

Reaction Steps

76.6 g of 3-cyano-2,4,5-trifluoro-benzoyl fluoride, together with 1 g of anhydrous aluminium chloride, are initially charged at 60-65° C., and 25 g of silicon tetrachloride are then added dropwise at the rate at which gas is given off. After the evolution of gas has ceased at 65° C., the mixture is distilled under reduced pressure. In the boiling range of 120-122° C./14 mbar, 73.2 g of 3-cyano-2,4,5-trifluoro-benzoyl chloride distil over.

Provenance & Evidence