huagongshe.com
HRID1595361

反应详情

EQUATION

反应方程式

HRID 1595361 的结构方程式

REACTANTS

反应物

2
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)c1nc(-c2cccc([N+](=O)[O-])c2)[nH]c1-c1ccc(OC)cc1
HCID178470188

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(-c2[nH]c(-c3cccc([N+](=O)[O-])c3)nc2C(=O)O)cc1
HCID178489035

未命名化合物

收率 77.3%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Ethyl 5-(4-methoxyphenyl)-2-(3-nitrophenyl)imidazole-4-carboxylate (13.3 g), ethyl alcohol (266 ml) and 1M aqueous sodium hydroxide solution (127 ml) were reacted and treated in the same manner as in Starting Material Synthetic Example 2 to give 5-(4-methoxyphenyl)-2-(3-nitrophenyl)imidazole-4-carboxyic acid (9.5 g), melting point 234-235° C.

WORKUP

后处理

  1. additiontreated in the same manner as