HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 4-(2-(Dimethylamino)ethyl)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Reactant | 2-(4-BROMOPHENYL)-N,N-DIMETHYLETHANAMINE | HCID 10751802 | — |
| Product | 4-(2-(Dimethylamino)ethyl)benzaldehyde | HCID 21704052 | — |
Reaction Steps
2-(4-Bromophenyl)-N,N-dimethylethylamine (6.8 g) was refluxed under heating with magnesium for 1 hr to prepare a Grignard reagent, which was reacted with DMF to give the objective 4-(2-dimethylaminoethyl)benzaldehyde as an oil (4.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06288061B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-3829d2f2230f418abd08f4b1fb067420 |
| Source note | uspto-grants-2001_09 |