Acetic Anhydride → HCID 178475833, compound

HRID 1595381Notes

Reaction equation

HRID 1595381 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:12][C:11]([C:13]3[CH:18]=[CH:17][C:16]([CH2:19][OH:20])=[CH:15][CH:14]=3)=[N:10][C:9]=2[C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])=[CH:4][CH:3]=1.[C:28](OC(=O)C)(=[O:30])[CH3:29]>N1C=CC=CC=1>[C:28]([O:20][CH2:19][C:16]1[CH:17]=[CH:18][C:13]([C:11]2[NH:12][C:8]([C:5]3[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=3)=[C:9]([C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])[N:10]=2)=[CH:14][CH:15]=1)(=[O:30])[CH3:29]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 178450798HCID 178450798, compound

Product 1

HCID 178475833HCID 178475833, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

tert-Butyl 5-(4-chlorophenyl)-2-(4-hydroxymethylphenyl)-imidazole-4-carboxylate is dissolved in pyridine and reacted with acetic anhydride to give the objective tert-butyl 2-(4-acetoxymethylphenyl)-5-(4-chlorophenyl)imidazole-4-carboxylate.

Sources & evidence

ORD record
ord-fd66e85ae52944f5a54fda676b4bdbdd
Source dataset
uspto-grants-2001_09
Patent number
US06288061B1

Reaction notes

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