Benzo(d)thiazol-2-amine → HCID 178424015, compound

HRID 1595390Notes

Reaction equation

HRID 1595390 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:12][C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[N:10][C:9]=2[C:19](O)=[O:20])=[CH:4][CH:3]=1.[NH2:22][C:23]1[S:24][C:25]2[CH:31]=[CH:30][CH:29]=[CH:28][C:26]=2[N:27]=1>>[S:24]1[C:25]2[CH:31]=[CH:30][CH:29]=[CH:28][C:26]=2[N:27]=[C:23]1[NH:22][C:19]([C:9]1[N:10]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[NH:12][C:8]=1[C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:7][CH:6]=1)=[O:20]

Participants

3

Reactant 2

HCID 8706Benzo(d)thiazol-2-amineHCID 178424017HCID 178424017, compound

Product 1

HCID 178424015HCID 178424015, compoundYield 6.8%

Procedure

5-(4-Methylphenyl)-2-phenylimidazole-4-carboxylic acid (0.5 g) and 2-aminobenzothiazole (0.35 g) were reacted and treated in the same manner as in Example 1 to give N-(benzothiazol-2-yl)-5-(4-methylphenyl)-2-phenylimidazole-4-carboxamide (0.05 g), melting point 269-270° C.

Workup

  1. additiontreated in the same manner as in Example 1

Sources & evidence

ORD record
ord-11b27993b944444fbe53da6e8024ca59
Source dataset
uspto-grants-2001_09
Patent number
US06288061B1

Reaction notes

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