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HRID1595421

反应详情

EQUATION

反应方程式

HRID 1595421 的结构方程式

REACTANTS

反应物

3
结构：Nc1nncs1
HCID19909

2-Amino-1,3,4-thiadiazole

C2H3N3S

结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：COc1ccc(-c2[nH]c(-c3cccc([N+](=O)[O-])c3)nc2C(=O)O)cc1
HCID178489035

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(-c2[nH]c(-c3cccc([N+](=O)[O-])c3)nc2C(=O)Nc2nncs2)cc1
HCID178489034

未命名化合物

PROCEDURE

实验过程

5-(4-Methoxyphenyl)-2-(3-nitrophenyl)imidazole-4-carboxylic acid, 1 M hydrochloric acid—ether solution, thionyl chloride and 2-amino-1,3,4-thiadiazole are reacted and treated in the same manner as in Example 1 to give 5-(4-methoxyphenyl)-2-(3-nitrophenyl)-N-(1,3,4-thiadiazol-2-yl)imidazole-4-carboxamide.

WORKUP

后处理

  1. additiontreated in the same manner as in Example 1