Sodium Hydroxide → HCID 178489050, compound

HRID 1595433Notes

Reaction equation

C([O:4][CH2:5][CH2:6][O:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[NH:15][C:16]([C:27]3[CH:32]=[CH:31][C:30]([O:33][CH3:34])=[CH:29][CH:28]=3)=[C:17]([C:19]([NH:21][C:22]3[S:23][CH:24]=[CH:25][N:26]=3)=[O:20])[N:18]=2)=[CH:10][CH:9]=1)(=O)C.[OH-].[Na+]>>[OH:4][CH2:5][CH2:6][O:7][C:8]1[CH:9]=[CH:10][C:11]([C:14]2[NH:15][C:16]([C:27]3[CH:28]=[CH:29][C:30]([O:33][CH3:34])=[CH:31][CH:32]=3)=[C:17]([C:19]([NH:21][C:22]3[S:23][CH:24]=[CH:25][N:26]=3)=[O:20])[N:18]=2)=[CH:12][CH:13]=1

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 178489051HCID 178489051, compound

Product 1

HCID 178489050HCID 178489050, compound

Procedure

2-(4-(2-Acetoxyethyloxy)phenyl)-5-(4-methoxyphenyl)-N-(2-thiazolyl)imidazole-4-carboxamide is hydrolyzed with sodium hydroxide to give 2-(4-(2-hydroxyethyloxy)phenyl)-5-(4-methoxyphenyl)-N-(2-thiazolyl)imidazole-4-carboxamide.

Sources & evidence

ORD record: ord-08e4611a2c484da6b04eb88bab7f77c0
Source dataset: uspto-grants-2001_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06288061B1

Reaction notes

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