Sodium Hydroxide → HCID 178522579, compound

HRID 1595435Notes

Reaction equation

HRID 1595435 reaction equation
C([O:4][CH2:5][CH2:6][O:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[NH:15][C:16]([C:27]3[CH:32]=[CH:31][C:30]([Cl:33])=[CH:29][CH:28]=3)=[C:17]([C:19]([NH:21][C:22]3[S:23][CH:24]=[CH:25][N:26]=3)=[O:20])[N:18]=2)=[CH:10][CH:9]=1)(=O)C.[OH-].[Na+]>>[Cl:33][C:30]1[CH:29]=[CH:28][C:27]([C:16]2[NH:15][C:14]([C:11]3[CH:10]=[CH:9][C:8]([O:7][CH2:6][CH2:5][OH:4])=[CH:13][CH:12]=3)=[N:18][C:17]=2[C:19]([NH:21][C:22]2[S:23][CH:24]=[CH:25][N:26]=2)=[O:20])=[CH:32][CH:31]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 1784764282-(4-(2-acetoxyethyloxy)phenyl)-5-(4-chlorophenyl)-N-(2-thiazolyl)imidazole-4-carboxamide

Product 1

HCID 178522579HCID 178522579, compound

Procedure

2-(4-(2-Acetoxyethyloxy)phenyl)-5-(4-chlorophenyl)-N-(2-thiazolyl)imidazole-4-carboxamide is hydrolyzed with sodium hydroxide to give 5-(4-chlorophenyl)-2-(4-(2-hydroxyethyloxy)-phenyl)-N-(2-thiazolyl)imidazole-4-carboxamide.

Sources & evidence

ORD record
ord-3c558c8abf8e4ba48d059a15da317b14
Source dataset
uspto-grants-2001_09
Patent number
US06288061B1

Reaction notes

Loading…