Methanol → 1-(Pyrrolidin-3-yl)pyrrolidine

HRID 159548Notes

Reaction equation

HRID 159548 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([N:13]2[CH2:14][CH2:15][CH2:16][CH2:17]2)[CH2:11][CH2:12]1.[CH3:20][OH:21].[H:18][H:19].[OH-:22].[OH-:24].[Pd+2:23]>>[NH:8]1[CH2:9][CH:10]([N:13]2[CH2:14][CH2:15][CH2:16][CH2:17]2)[CH2:11][CH2:12]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 231459231'-Benzyl-[1,3']bipyrrolidinylHCID 178418361HCID 178418361, compound

Product 1

HCID 146273751-(Pyrrolidin-3-yl)pyrrolidine

Sources & evidence

ORD record
ord-9a9d4840003f49d0a01887714ee32644
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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