4-Methoxybenzenesulfonyl chloride → HCID 21705015, compound

Participants

Reaction Steps

2.76 g (20 mmole) p-hydroxyphenethyl alcohol was dissolved in 80 ml dichloromethane. 6 g triethylamine, 8.5 g (41 mmole) 4-methoxybenzenesulfonyl chloride and 0.2 g 4-dimethyl-aminopyridine were added. The mixture was stirred over night at room temperature and filtered through silica gel with dichloromethane as eluent to give 8.5 g (yield 89%) of 4-(4-methoxyphenylsulfonyloxy)phenethyl 4-methoxy-1-benzenesulfonate.

Provenance & Evidence