Hydrochloric Acid → 4-[2-(4-Aminophenyl)ethoxy]benzaldehyde

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Hydrochloric Acid	HCID 313	—
Edukt	tert-butyl N-{4-[2-(4-formylphenoxy)ethyl]phenyl}carbamate	HCID 21704970	—
Lösungsmittel	Ethyl Acetate	HCID 8857	—
Produkt	4-[2-(4-Aminophenyl)ethoxy]benzaldehyde	HCID 21705003	141,9%

Reaktionsschritte

5 g (14.6 mmole) tert-butyl N-{4-[2-(4-formylphenoxy)ethyl]phenyl}carbamate was deprotected in ethyl acetate saturated with hydrochloric acid at room temperature over night. The product precipitated and filtration yielded 5 g (100%) of 4-[2-(4-aminophenyl)ethoxy]benzaldehyde x HCl. The product contained some solvent, but was used without further purification.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US06288096B1
Quelldatensatz	uspto-grants-2001_09
ORD ID	ord-3852a4ec30f447a98636b3b2dc37171d
Quellennotiz	uspto-grants-2001_09