HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 54012500, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Thiazolidinedione | HCID 5437 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | HCID 21705020 | HCID 21705020 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 54012500 | HCID 54012500 | 71.2% |
Reaction Steps
2 g (6.7 mmole) methyl N-{4-[2-(4-formylphenoxy)ethyl]phenyl}carbamate, 1.57 g (13.4 mmole) 2,4-thiazolidinedione, piperidine, acetic acid and toluene were refluxed with water separation in a Dean-Stark apparatus for 3 hours. The formed yellow precipitate was collected by filtration giving 1.9 g (yield 71.2%) of 5-(4-[2-(4-methoxycarbonylaminophenyl)ethoxy]benzylidene)thiazolidine-2,4-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06288096B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-e47c9648506e47f28ed179e19fb3a9f9 |
| Source note | uspto-grants-2001_09 |