4-Hydroxybenzaldehyde → HCID 21704999, compound

Participants

Reaction Steps

9.3 g (31.6 mmole) 3-(methylsulfonyloxy)phenethyl methanesulfonate, 9.91 g (82 mmole) p-hydroxybenzaldehyde and 13 g (94.8 mmole) potassium carbonate in 200 ml acetonitrile were refluxed for 4 hours. The precipitate was filtered off and the solvent was evaporated in vacuo. Dichloromethane was added and the organic phase was washed with water, dried (magnesium sulfate), filtered and the solvent was evaporated to give 8.72 g (yield 88%) of 3-[2-(4-formylphenoxy)ethyl]phenyl methanesulfonate.

Provenance & Evidence