4-Hydroxybenzaldehyde → HCID 21705009, compound

Participants

Reaction Steps

A mixture of 0.85 g (2.11 mmole) of 4-(trifluoromethylsulfonyloxy)phenethyl trifluoromethansulfonate, 0.27 g (2.2 mmole) p-hydroxybenzaldehyde and 0.72 g (2.2 mmole) cesium carbonate in acetonitrile was stirred at room temperature over night. The salts were filtered off and the solvent evaporated in vacuo. Purification by chromatography on silica gel using dichloromethane as eluent gave 0.6 g (yield 75%) of 4-[2-(4-formylphenoxy)ethyl]phenyl trifluoromethanesulfonate.

Provenance & Evidence